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Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy

Aldo–keto reductases comprise of AKR1C1–AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. Recent studies have provided evidences of strong correlation between the expression levels of these family memb...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zeng, Chen-Ming, Chang, Lin-Lin, Ying, Mei-Dan, Cao, Ji, He, Qiao-Jun, Zhu, Hong, Yang, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349110/
https://ncbi.nlm.nih.gov/pubmed/28352233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00119
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