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Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy

Aldo–keto reductases comprise of AKR1C1–AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. Recent studies have provided evidences of strong correlation between the expression levels of these family memb...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Zeng, Chen-Ming, Chang, Lin-Lin, Ying, Mei-Dan, Cao, Ji, He, Qiao-Jun, Zhu, Hong, Yang, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349110/
https://ncbi.nlm.nih.gov/pubmed/28352233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00119
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