Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging

Defects in mitochondrial biogenesis and function are common in many neurodegenerative disorders, including Huntington’s disease (HD). We have previously shown that in yeast models of HD, enhancement of mitochondrial biogenesis through overexpression of Hap4, the catalytic subunit of the transcriptio...

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Detaylı Bibliyografya
Yayımlandı:Microb Cell
Asıl Yazarlar: Ruetenik, Andrea L., Ocampo, Alejandro, Ruan, Kai, Zhu, Yi, Li, Chong, Zhai, R. Grace, Barrientos, Antoni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Shared Science Publishers OG 2016
Konular:
Microbiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349013/
https://ncbi.nlm.nih.gov/pubmed/28357370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2016.08.518
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