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Genetic and molecular analysis of chlorambucil-induced germ-line mutations in the mouse.

Eighteen variants recovered from specific locus mutation rate experiments involving the mutagen chlorambucil were subjected to several genetic and molecular analyses. Most mutations were found to be homozygous lethal. Because lethality is often presumptive evidence for multilocus-deletion events, 10...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Principais autores: Rinchik, E M, Bangham, J W, Hunsicker, P R, Cacheiro, N L, Kwon, B S, Jackson, I J, Russell, L B
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 1990
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304907/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1416
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