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Chlorambucil-induced mutations in mice recovered in homozygotes.

Chlorambucil induced a number of recessive visible mutations in the mouse. Induction of these mutations was studied in two mating schemes, each designed to recover mutations after two intercrosses. In scheme 1, 10 mutations were detected in 82 mice; in scheme 2, 1 mutation was detected in 19 mice. W...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Flaherty, L, Messer, A, Russell, L B, Rinchik, E M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48762/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2859
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