Mouse Lung Fibroblast Resistance to Fas-Mediated Apoptosis Is Dependent on the Baculoviral Inhibitor of Apoptosis Protein 4 and the Cellular FLICE-Inhibitory Protein

A characteristic feature of idiopathic pulmonary fibrosis (IPF) is accumulation of apoptotic resistant fibroblasts/myofibroblasts in the fibroblastic foci. As caveolin (Cav)-null mice develop pulmonary fibrosis (PF), we hypothesized that the participating fibroblasts display an apoptosis-resistant p...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Predescu, Sanda A., Zhang, Jian, Bardita, Cristina, Patel, Monal, Godbole, Varun, Predescu, Dan N.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348516/
https://ncbi.nlm.nih.gov/pubmed/28352235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00128
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