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Cellular FLICE-like Inhibitory Protein Deviates Myofibroblast Fas-Induced Apoptosis Toward Proliferation during Lung Fibrosis

A prominent feature of fibrotic tissue in general and of lungs in particular is fibroblast proliferation and accumulation. In patients overcoming fibrosis, apoptosis limits this excessive cell growth. We have previously shown resistance to Fas-induced apoptosis of primary lung fibroblasts from mice...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Golan-Gerstl, Regina, Wallach-Dayan, Shulamit B., Zisman, Philip, Cardoso, Wellington V., Goldstein, Ronald H., Breuer, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460908/
https://ncbi.nlm.nih.gov/pubmed/22582174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0284RC
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