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Cellular FLICE-like Inhibitory Protein Deviates Myofibroblast Fas-Induced Apoptosis Toward Proliferation during Lung Fibrosis

A prominent feature of fibrotic tissue in general and of lungs in particular is fibroblast proliferation and accumulation. In patients overcoming fibrosis, apoptosis limits this excessive cell growth. We have previously shown resistance to Fas-induced apoptosis of primary lung fibroblasts from mice...

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Publicat a:Am J Respir Cell Mol Biol
Autors principals: Golan-Gerstl, Regina, Wallach-Dayan, Shulamit B., Zisman, Philip, Cardoso, Wellington V., Goldstein, Ronald H., Breuer, Raphael
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460908/
https://ncbi.nlm.nih.gov/pubmed/22582174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0284RC
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