Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response

Lung fibrosis is characterized by abnormal accumulation of fibroblasts in the interstitium of the alveolar space. Two populations of myofibroblasts, distinguished by Thy1 expression, are detected in human and murine lungs. Accumulation of Thy1-negative (Thy1(−)) myofibroblasts was shown in the lungs...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Cohen, Pazit Y., Breuer, Raphael, Zisman, Philip, Wallach-Dayan, Shulamit B.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537759/
https://ncbi.nlm.nih.gov/pubmed/26300593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/942179
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