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Bleomycin-Treated Chimeric Thy1-Deficient Mice with Thy1-Deficient Myofibroblasts and Thy-Positive Lymphocytes Resolve Inflammation without Affecting the Fibrotic Response

Lung fibrosis is characterized by abnormal accumulation of fibroblasts in the interstitium of the alveolar space. Two populations of myofibroblasts, distinguished by Thy1 expression, are detected in human and murine lungs. Accumulation of Thy1-negative (Thy1(−)) myofibroblasts was shown in the lungs...

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Bibliografski detalji
Izdano u:Mediators Inflamm
Glavni autori: Cohen, Pazit Y., Breuer, Raphael, Zisman, Philip, Wallach-Dayan, Shulamit B.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537759/
https://ncbi.nlm.nih.gov/pubmed/26300593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/942179
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