Combinatorial effects of doxorubicin and retargeted tissue factor by intratumoral entrapment of doxorubicin and proapoptotic increase of tumor vascular infarction

Truncated tissue factor (tTF), retargeted to tumor vasculature by GNGRAHA peptide (tTF-NGR), and doxorubicin have therapeutic activity against a variety of tumors. We report on combination experiments of both drugs using different schedules. We have tested fluorescence- and HPLC-based intratumoral p...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Stucke-Ring, Janine, Ronnacker, Julian, Brand, Caroline, Höltke, Carsten, Schliemann, Christoph, Kessler, Torsten, Schmidt, Lars Henning, Harrach, Saliha, Mantke, Verena, Hintelmann, Heike, Hartmann, Wolfgang, Wardelmann, Eva, Lenz, Georg, Wünsch, Bernhard, Müller-Tidow, Carsten, Mesters, Rolf M., Schwöppe, Christian, Berdel, Wolfgang E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347705/
https://ncbi.nlm.nih.gov/pubmed/27738341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12559
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky