ATM is the primary kinase responsible for phosphorylation of Hsp90α after ionizing radiation

Heat shock protein 90 is a chaperone that plays an essential role in the stabilization of a large number of signal transduction molecules, many of which are associated with oncogenesis. An Hsp90 isoform (Hsp90α) has been shown to be selectively phosphorylated on two N-terminal threonine residues (th...

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Udgivet i:Oncotarget
Main Authors: Elaimy, Ameer L., Ahsan, Aarif, Marsh, Katherine, Pratt, William B., Ray, Dipankar, Lawrence, Theodore S., Nyati, Mukesh K.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347704/
https://ncbi.nlm.nih.gov/pubmed/27738310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12557
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