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PLCε1 regulates SDF-1α–induced lymphocyte adhesion and migration to sites of inflammation
Regulation of integrins is critical for lymphocyte adhesion to endothelium and migration throughout the body. Inside-out signaling to integrins is mediated by the small GTPase Ras-proximate-1 (Rap1). Using an RNA-mediated interference screen, we identified phospholipase Cε 1 (PLCε1) as a crucial reg...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347583/ https://ncbi.nlm.nih.gov/pubmed/28213494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612900114 |
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