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PLCε1 suppresses tumor growth by regulating murine T cell mobilization
Phospholipase C epsilon 1 (PLCε1) is a unique member of the phospholipase family, in that it also functions as a guanine nucleotide exchange factor (GEF) for the small GTPase Rap1. It is this function as a Rap1 GEF that gives PLCε1 an essential role in chemokine‐mediated T cell adhesion. We have uti...
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| Published in: | Clin Exp Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066383/ https://ncbi.nlm.nih.gov/pubmed/31867717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13409 |
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