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c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1
Angiogenesis is regulated by highly coordinated action of various proteins with pro- and anti-angiogenic functions. Among the many cytoplasmic signaling proteins that are activated by VEGFR-2, activation of PLCγ1 is considered to play a pivotal role in angiogenic signaling. In previous study we have...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969724/ https://ncbi.nlm.nih.gov/pubmed/21242968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.597 |
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