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The C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis
Insulin-like growth factor-binding protein 5 (IGFBP-5) plays a role in cell growth, differentiation, and apoptosis. In this study, we found that IGFBP5 was markedly downregulated in ovarian cancer tissue. We investigated the functional significance of IGFBP-5 as a tumor suppressor. To determine func...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5180245/ https://ncbi.nlm.nih.gov/pubmed/28008951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39334 |
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