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c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1

Angiogenesis is regulated by highly coordinated action of various proteins with pro- and anti-angiogenic functions. Among the many cytoplasmic signaling proteins that are activated by VEGFR-2, activation of PLCγ1 is considered to play a pivotal role in angiogenic signaling. In previous study we have...

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Bibliographic Details
Main Authors: Meyer, Rosana D, Husain, Deeba, Rahimi, Nader
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969724/
https://ncbi.nlm.nih.gov/pubmed/21242968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.597
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