The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
The toroidal damage checkpoint complex Rad9–Rad1–Hus1 (9-1-1) has been characterized as a sensor of DNA damage. Flap endonuclease 1 (FEN1) is a structure-specific nuclease involved both in removing initiator RNA from Okazaki fragments and in DNA repair pathways. FEN1 activity is stimulated by prolif...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15556996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0407686101 |
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