The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1

The toroidal damage checkpoint complex Rad9–Rad1–Hus1 (9-1-1) has been characterized as a sensor of DNA damage. Flap endonuclease 1 (FEN1) is a structure-specific nuclease involved both in removing initiator RNA from Okazaki fragments and in DNA repair pathways. FEN1 activity is stimulated by prolif...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Wang, Wensheng, Brandt, Patrick, Rossi, Marie L., Lindsey-Boltz, Laura, Podust, Vladimir, Fanning, Ellen, Sancar, Aziz, Bambara, Robert A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC534749/
https://ncbi.nlm.nih.gov/pubmed/15556996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407686101
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы