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Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

The human DNA damage sensors, Rad17-replication factor C (Rad17-RFC) and the Rad9-Rad1-Hus1 (9-1-1) checkpoint complex, are thought to be involved in the early steps of the DNA damage checkpoint response. Rad17-RFC and the 9-1-1 complex have been shown to be structurally similar to the replication f...

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Bibliografiske detaljer
Main Authors: Bermudez, Vladimir P., Lindsey-Boltz, Laura A., Cesare, Anthony J., Maniwa, Yoshimasa, Griffith, Jack D., Hurwitz, Jerard, Sancar, Aziz
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149884/
https://ncbi.nlm.nih.gov/pubmed/12578958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0437927100
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