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Enantioselective amine α-functionalization via palladium catalyzed C–H arylation of thioamides
Saturated aza-heterocycles are highly privileged building blocks that are commonly encountered in bioactive compounds and approved therapeutic agents. These N-heterocycles are also incorporated as chiral auxiliaries and ligands in asymmetric synthesis. As such, development of methods to functionaliz...
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| Publicado no: | Nat Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347480/ https://ncbi.nlm.nih.gov/pubmed/28282045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2619 |
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