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Enantioselective amine α-functionalization via palladium catalyzed C–H arylation of thioamides

Saturated aza-heterocycles are highly privileged building blocks that are commonly encountered in bioactive compounds and approved therapeutic agents. These N-heterocycles are also incorporated as chiral auxiliaries and ligands in asymmetric synthesis. As such, development of methods to functionaliz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Chem
Prif Awduron: Jain, Pankaj, Verma, Pritha, Xia, Guoqin, Yu, Jin-Quan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347480/
https://ncbi.nlm.nih.gov/pubmed/28282045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2619
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