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The molecular program induced in T cells undergoing homeostatic proliferation

Naïve T cells proliferate independently of cognate antigen when introduced into lymphopenic hosts. Lymphopenia-induced proliferation depends on low-affinity MHC/self-peptide complexes and on IL-7. To elucidate the intracellular signals mediating this proliferation, we analyzed changes in gene expres...

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Autors principals: Goldrath, Ananda W., Luckey, C. John, Park, Richard, Benoist, Christophe, Mathis, Diane
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC534746/
https://ncbi.nlm.nih.gov/pubmed/15548615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407417101
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