Conditional Alpl Ablation Phenocopies Dental Defects of Hypophosphatasia

Loss-of-function mutations in ALPL result in hypophosphatasia (HPP), an inborn error of metabolism that causes defective skeletal and dental mineralization. ALPL encodes tissue-nonspecific alkaline phosphatase, an enzyme expressed in bone, teeth, liver, and kidney that hydrolyzes the mineralization...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Dent Res
Main Authors: Foster, B.L., Kuss, P., Yadav, M.C., Kolli, T.N., Narisawa, S., Lukashova, L., Cory, E., Sah, R.L., Somerman, M.J., Millán, J.L.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347426/
https://ncbi.nlm.nih.gov/pubmed/27582029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034516663633
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker