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Tooth root dentin mineralization defects in a mouse model of hypophosphatasia
Tissue-nonspecific alkaline phosphatase (TNAP) is expressed in mineralizing tissues and functions to reduce pyrophosphate (PP(i)), a potent inhibitor of mineralization. Loss of TNAP function causes hypophosphatasia (HPP), a heritable disorder marked by increased PP(i), resulting in rickets and osteo...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3541444/ https://ncbi.nlm.nih.gov/pubmed/22991301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1767 |
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