Tooth root dentin mineralization defects in a mouse model of hypophosphatasia

Tissue-nonspecific alkaline phosphatase (TNAP) is expressed in mineralizing tissues and functions to reduce pyrophosphate (PP(i)), a potent inhibitor of mineralization. Loss of TNAP function causes hypophosphatasia (HPP), a heritable disorder marked by increased PP(i), resulting in rickets and osteo...

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書誌詳細
主要な著者: Foster, B.L., Nagatomo, K.J., Tso, H.W., Tran, A.B., Nociti, F.H., Narisawa, S., Yadav, M.C., McKee, M.D., Millán, J.L., Somerman, M.J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541444/
https://ncbi.nlm.nih.gov/pubmed/22991301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1767
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