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Enzyme replacement prevents enamel defects in hypophosphatasia mice
Hypophosphatasia (HPP) is the inborn error of metabolism characterized by deficiency of alkaline phosphatase activity leading to rickets or osteomalacia and to dental defects. HPP occurs from loss-of-function mutations within the gene that encodes the tissue-nonspecific isozyme of alkaline phosphata...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395779/ https://ncbi.nlm.nih.gov/pubmed/22461224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1619 |
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