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Solution structure of the CD3εδ ectodomain and comparison with CD3εγ as a basis for modeling T cell receptor topology and signaling
Invariant CD3 subunit dimers (CD3εγ, CD3εδ, and CD3ζζ) are the signaling components of the αβ T cell receptor (TCR). The recently solved structure of murine CD3εγ revealed a unique side-to-side interface and central β-sheets conjoined between the two C2-set Ig-like ectodomains, with the pairing of t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC534738/ https://ncbi.nlm.nih.gov/pubmed/15557001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407576101 |
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