Loading...

Solution structure of the CD3εδ ectodomain and comparison with CD3εγ as a basis for modeling T cell receptor topology and signaling

Invariant CD3 subunit dimers (CD3εγ, CD3εδ, and CD3ζζ) are the signaling components of the αβ T cell receptor (TCR). The recently solved structure of murine CD3εγ revealed a unique side-to-side interface and central β-sheets conjoined between the two C2-set Ig-like ectodomains, with the pairing of t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Sun, Zhen-Yu J., Kim, Sun Taek, Kim, Il Chul, Fahmy, Amr, Reinherz, Ellis L., Wagner, Gerhard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC534738/
https://ncbi.nlm.nih.gov/pubmed/15557001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407576101
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!