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The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function
Self versus non-self discrimination is at the core of T lymphocyte recognition. To this end, αβ T-cell receptors (TCRs) ligate ‘foreign’ peptides bound to major histocompatibility complex (MHC) class I or class II molecules (pMHC) arrayed on the surface of antigen-presenting cells (APCs). Since the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694212/ https://ncbi.nlm.nih.gov/pubmed/23046125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2012.01161.x |
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