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αβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapy

αβ T lymphocytes sense perturbations in host cellular body components induced by infectious pathogens, oncogenic transformation or chemical or physical damage. Millions-billions of these lymphocytes are generated through T-lineage development in the thymus, each endowed with a clonally-restricted su...

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Détails bibliographiques
Publié dans:Cancer Immunol Res
Auteur principal: Reinherz, Ellis L.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4391277/
https://ncbi.nlm.nih.gov/pubmed/25847967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0042
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