The molecular bases of δ/αβ T cell–mediated antigen recognition

αβ and γδ T cells are disparate T cell lineages that can respond to distinct antigens (Ags) via the use of the αβ and γδ T cell Ag receptors (TCRs), respectively. Here we characterize a population of human T cells, which we term δ/αβ T cells, expressing TCRs comprised of a TCR-δ variable gene (Vδ1)...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Pellicci, Daniel G., Uldrich, Adam P., Le Nours, Jérôme, Ross, Fiona, Chabrol, Eric, Eckle, Sidonia B.G., de Boer, Renate, Lim, Ricky T., McPherson, Kirsty, Besra, Gurdyal, Howell, Amy R., Moretta, Lorenzo, McCluskey, James, Heemskerk, Mirjam H.M., Gras, Stephanie, Rossjohn, Jamie, Godfrey, Dale I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267242/
https://ncbi.nlm.nih.gov/pubmed/25452463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141764
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