Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

Studies on the biology of mucosal-associated invariant T cells (MAIT cells) in mice have been hampered by a lack of specific reagents. Using MR1-antigen (Ag) tetramers that specifically bind to the MR1-restricted MAIT T cell receptors (TCRs), we demonstrate that MAIT cells are detectable in a broad...

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Publicado no:J Exp Med
Main Authors: Rahimpour, Azad, Koay, Hui Fern, Enders, Anselm, Clanchy, Rhiannon, Eckle, Sidonia B.G., Meehan, Bronwyn, Chen, Zhenjun, Whittle, Belinda, Liu, Ligong, Fairlie, David P., Goodnow, Chris C., McCluskey, James, Rossjohn, Jamie, Uldrich, Adam P., Pellicci, Daniel G., Godfrey, Dale I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493408/
https://ncbi.nlm.nih.gov/pubmed/26101265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142110
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