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Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules
Intracellular protein interaction domains are essential for eukaryotic signaling. In T cells, the CD2BP2 adaptor binds two membrane-proximal proline-rich motifs in the CD2 cytoplasmic tail via its GYF domain, thereby regulating interleukin-2 production. Here we present the structure of the GYF domai...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137194/ https://ncbi.nlm.nih.gov/pubmed/12426371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf602 |
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