Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules
Intracellular protein interaction domains are essential for eukaryotic signaling. In T cells, the CD2BP2 adaptor binds two membrane-proximal proline-rich motifs in the CD2 cytoplasmic tail via its GYF domain, thereby regulating interleukin-2 production. Here we present the structure of the GYF domai...
Uloženo v:
| Vydáno v: | EMBO J |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12426371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf602 |
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