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Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores

The replication timing of some genes is developmentally regulated, but the significance of replication timing to cellular differentiation has been difficult to substantiate. Studies have largely been restricted to the comparison of a few genes in established cell lines derived from different tissues...

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Hlavní autoři: Hiratani, Ichiro, Leskovar, Amanda, Gilbert, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC534734/
https://ncbi.nlm.nih.gov/pubmed/15557005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406687101
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