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A Possible Role for Long Interspersed Nuclear Elements-1 (LINE-1) in Huntington’s Disease Progression

BACKGROUND: Recent studies have shown that increased mobilization of Long Interspersed Nuclear Elements-1 (L1) can promote the pathophysiology of multiple neurological diseases. However, its role in Huntington’s disease (HD) remains unknown. MATERIAL/METHODS: R6/2 mice – a common mouse model of HD –...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Tan, Huiping, Wu, Chunlin, Jin, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007493/
https://ncbi.nlm.nih.gov/pubmed/29851926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.907328
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