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Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications
Epigenetic changes in long interspersed nuclear element-1s (LINE-1s or L1s) occur early during the process of carcinogenesis. A lower methylation level (hypomethylation) of LINE-1 is common in most cancers, and the methylation level is further decreased in more advanced cancers. Consequently, severa...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365388/ https://ncbi.nlm.nih.gov/pubmed/22704344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13148-011-0032-8 |
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