Hypomethylation of long interspersed nuclear element-1 promoter is associated with poor outcomes for curative resected hepatocellular carcinoma

BACKGROUND: Epigenetic alterations are well documented in hepatocarcinogenesis. However, hypomethylation of long interspersed nuclear element 1(LINE-1) promoter and its relationship with clinicopathological features in hepatocellular carcinoma (HCC) remain unknown. METHODS: The bisulfite-specific PC...

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Vydáno v:Liver Int
Hlavní autoři: Gao, Xu-dong, Qu, Jian-hui, Chang, Xiu-juan, Lu, Yin-ying, Bai, Wen-lin, Wang, Hong, Xu, Zhong-xian, An, Lin-jing, Wang, Chun-ping, Zeng, Zhen, Yang, Yong-ping
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Liver Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238827/
https://ncbi.nlm.nih.gov/pubmed/23875825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12264
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