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Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores

The replication timing of some genes is developmentally regulated, but the significance of replication timing to cellular differentiation has been difficult to substantiate. Studies have largely been restricted to the comparison of a few genes in established cell lines derived from different tissues...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hiratani, Ichiro, Leskovar, Amanda, Gilbert, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC534734/
https://ncbi.nlm.nih.gov/pubmed/15557005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406687101
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