DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation

Aberrant DNA methylation has been frequently observed in many human cancers, including rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children. To date, the expression and function of the de novo DNA methyltransferase (DNMT) 3B in RMS have not yet been investigated. Our study show fo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Megiorni, Francesca, Camero, Simona, Ceccarelli, Simona, McDowell, Heather P., Mannarino, Olga, Marampon, Francesco, Pizer, Barry, Shukla, Rajeev, Pizzuti, Antonio, Marchese, Cinzia, Clerico, Anna, Dominici, Carlo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346718/
https://ncbi.nlm.nih.gov/pubmed/27764816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12688
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