Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells

Wnt signaling is implicated in bone formation and activated in breast cancer cells promoting primary and metastatic tumor growth. A compelling question is whether osteogenic miRNAs that increase Wnt activity for bone formation are aberrantly expressed in breast tumor cells to support metastatic bone...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Taipaleenmäki, Hanna, Farina, Nicholas H., van Wijnen, Andre J., Stein, Janet L., Hesse, Eric, Stein, Gary S., Lian, Jane B.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346696/
https://ncbi.nlm.nih.gov/pubmed/27738322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12593
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