Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells

Wnt signaling is implicated in bone formation and activated in breast cancer cells promoting primary and metastatic tumor growth. A compelling question is whether osteogenic miRNAs that increase Wnt activity for bone formation are aberrantly expressed in breast tumor cells to support metastatic bone...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Taipaleenmäki, Hanna, Farina, Nicholas H., van Wijnen, Andre J., Stein, Janet L., Hesse, Eric, Stein, Gary S., Lian, Jane B.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346696/
https://ncbi.nlm.nih.gov/pubmed/27738322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12593
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