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Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells

Wnt signaling is implicated in bone formation and activated in breast cancer cells promoting primary and metastatic tumor growth. A compelling question is whether osteogenic miRNAs that increase Wnt activity for bone formation are aberrantly expressed in breast tumor cells to support metastatic bone...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Taipaleenmäki, Hanna, Farina, Nicholas H., van Wijnen, Andre J., Stein, Janet L., Hesse, Eric, Stein, Gary S., Lian, Jane B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346696/
https://ncbi.nlm.nih.gov/pubmed/27738322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12593
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