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The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells
Notch signaling plays a key role in osteoblast differentiation. A major transcriptional downstream regulator of this pathway is the Helix-Loop-Helix (HLH) transcription factor Hairy/Enhancer of Split 1 (Hes-1). Here we investigated the function of Hes-1 in osteoblastic cells. Endogenous Hes-1 gene e...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150580/ https://ncbi.nlm.nih.gov/pubmed/19670267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22299 |
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