Bone-Specific Transcription Factor Runx2 Interacts with the 1α,25-Dihydroxyvitamin D(3) Receptor To Up-Regulate Rat Osteocalcin Gene Expression in Osteoblastic Cells

Bone-specific transcription of the osteocalcin (OC) gene is regulated principally by the Runx2 transcription factor and is further stimulated in response to 1α,25-dihydroxyvitamin D(3) via its specific receptor (VDR). The rat OC gene promoter contains three recognition sites for Runx2 (sites A, B, a...

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Detalhes bibliográficos
Main Authors: Paredes, Roberto, Arriagada, Gloria, Cruzat, Fernando, Villagra, Alejandro, Olate, Juan, Zaidi, Kaleem, van Wijnen, Andre, Lian, Jane B., Stein, Gary S., Stein, Janet L., Montecino, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517904/
https://ncbi.nlm.nih.gov/pubmed/15456860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.8847-8861.2004
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