miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells

MicroRNAs (miRNAs) negatively and post-transcriptionally regulate expression of multiple target genes to support anabolic pathways for bone formation. Here, we show that miR-218 is induced during osteoblast differentiation and has potent osteogenic properties. miR-218 promotes commitment and differe...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Hassan, Mohammad Q., Maeda, Yukiko, Taipaleenmaki, Hanna, Zhang, Weibing, Jafferji, Mohammad, Gordon, Jonathan A. R., Li, Zhaoyong, Croce, Carlo M., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
Onderwerpen:
Cell Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516754/
https://ncbi.nlm.nih.gov/pubmed/23060446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377515
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items