miR-218 Directs a Wnt Signaling Circuit to Promote Differentiation of Osteoblasts and Osteomimicry of Metastatic Cancer Cells

MicroRNAs (miRNAs) negatively and post-transcriptionally regulate expression of multiple target genes to support anabolic pathways for bone formation. Here, we show that miR-218 is induced during osteoblast differentiation and has potent osteogenic properties. miR-218 promotes commitment and differe...

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מידע ביבליוגרפי
Main Authors: Hassan, Mohammad Q., Maeda, Yukiko, Taipaleenmaki, Hanna, Zhang, Weibing, Jafferji, Mohammad, Gordon, Jonathan A. R., Li, Zhaoyong, Croce, Carlo M., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Lian, Jane B.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
Cell Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516754/
https://ncbi.nlm.nih.gov/pubmed/23060446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377515
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