Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130

The retinoblastoma gene family consists of three genes: RB, p107, and p130. While loss of pRB causes retinoblastoma in humans and pituitary gland tumors in mice, tumorigenesis in other tissues may be suppressed by p107 and p130. To test this hypothesis, we have generated chimeric mice from embryonic...

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Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Dannenberg, Jan-Hermen, Schuijff, Leontine, Dekker, Marleen, van der Valk, Martin, Riele, Hein te
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2004
Soggetti:	Research Papers
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.322004
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