Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes

BACKGROUND: Airway fibrosis is one of the pathological features of chronic obstructive pulmonary disease (COPD), and recent studies revealed that acetylcholine plays an important role in the development of airway remodeling by stimulating proliferation and collagen synthesis of lung fibroblasts. Thi...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Namba, Yukiko, Togo, Shinsaku, Tulafu, Miniwan, Kadoya, Kotaro, Nagahama, Kumi Yoneda, Taka, Hikari, Kaga, Naoko, Orimo, Akira, Liu, Xiangde, Takahashi, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346259/
https://ncbi.nlm.nih.gov/pubmed/28284212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0529-6
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