Combination of glycopyrronium and indacaterol inhibits carbachol-induced ERK5 signal in fibrotic processes

BACKGROUND: Airway fibrosis is one of the pathological features of chronic obstructive pulmonary disease (COPD), and recent studies revealed that acetylcholine plays an important role in the development of airway remodeling by stimulating proliferation and collagen synthesis of lung fibroblasts. Thi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Respir Res
Auteurs principaux: Namba, Yukiko, Togo, Shinsaku, Tulafu, Miniwan, Kadoya, Kotaro, Nagahama, Kumi Yoneda, Taka, Hikari, Kaga, Naoko, Orimo, Akira, Liu, Xiangde, Takahashi, Kazuhisa
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346259/
https://ncbi.nlm.nih.gov/pubmed/28284212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0529-6
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