Local Effects of Human PCSK9 on the Atherosclerotic Lesion

Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) promotes atherosclerosis by increasing low-density lipoprotein (LDL) cholesterol levels through degradation of hepatic LDL receptors (LDLR). Studies have described the systemic effects of PCSK9 on atherosclerosis, but whether PCSK9 has local and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pathol
Prif Awduron: Giunzioni, Ilaria, Tavori, Hagai, Covarrubias, Roman, Major, Amy S., Ding, Lei, Zhang, Youmin, DeVay, Rachel M., Hong, Liang, Fan, Daping, Predazzi, Irene M., Rashid, Shirya, Linton, MacRae F., Fazio, Sergio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346023/
https://ncbi.nlm.nih.gov/pubmed/26333678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4630
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