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PCSK9 inhibition to reduce cardiovascular disease risk: recent findings from the biology of PCSK9

PURPOSE OF REVIEW: Review novel insights into the biology of proprotein convertase subtilisin/kexin 9 (PCSK9) that may explain the extreme efficiency of PCSK9 inhibition and the unexpected metabolic effects resulting from PCSK9 monoclonal antibody therapy, and may identify additional patients as tar...

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Detalhes bibliográficos
Publicado no:Curr Opin Endocrinol Diabetes Obes
Main Authors: Tavori, Hagai, Giunzioni, Ilaria, Fazio, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384821/
https://ncbi.nlm.nih.gov/pubmed/25692926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MED.0000000000000137
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