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On the Function and Homeostasis of PCSK9: Reciprocal Interaction with LDLR and Additional Lipid Effects
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a circulatory ligand that terminates the lifecycle of the low-density lipoprotein (LDL) receptor (LDLR) thus affecting plasma LDL-cholesterol (LDL-C) levels. Recent evidence shows that in addition to the straightforward mechanism of action, th...
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| Publicado no: | Atherosclerosis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4562333/ https://ncbi.nlm.nih.gov/pubmed/25544176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2014.12.017 |
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