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On the Function and Homeostasis of PCSK9: Reciprocal Interaction with LDLR and Additional Lipid Effects

Proprotein convertase subtilisin kexin type 9 (PCSK9) is a circulatory ligand that terminates the lifecycle of the low-density lipoprotein (LDL) receptor (LDLR) thus affecting plasma LDL-cholesterol (LDL-C) levels. Recent evidence shows that in addition to the straightforward mechanism of action, th...

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Publicado en:Atherosclerosis
Autores principales: Tavori, Hagai, Rashid, Shirya, Fazio, Sergio
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562333/
https://ncbi.nlm.nih.gov/pubmed/25544176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2014.12.017
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