Local Effects of Human PCSK9 on the Atherosclerotic Lesion

Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) promotes atherosclerosis by increasing low-density lipoprotein (LDL) cholesterol levels through degradation of hepatic LDL receptors (LDLR). Studies have described the systemic effects of PCSK9 on atherosclerosis, but whether PCSK9 has local and...

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Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Giunzioni, Ilaria, Tavori, Hagai, Covarrubias, Roman, Major, Amy S., Ding, Lei, Zhang, Youmin, DeVay, Rachel M., Hong, Liang, Fan, Daping, Predazzi, Irene M., Rashid, Shirya, Linton, MacRae F., Fazio, Sergio
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346023/
https://ncbi.nlm.nih.gov/pubmed/26333678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4630
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